Abstract:
While researching on the staphylococcal variants in
1928, A. Fleming found that the propagation of bacteria
being suppressed in culture media stained with
mildews. It was named penicillin after the nomenclature
of penicillium to which the material produced by
mildews belonged, heralding the start of penicillin.
Studies on this material in terms of bacteriostatic
agent rapidly progressed thereafter to make its industrial
mass production possible. Meanwhile, various
other derivatives of penicillin have been produced with
its mother nucleus 6-APA as a starting material.